Temporal lobe impairment in West syndrome: Event-related potential evidence

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Temporal Lobe Impairment in West Syndrome: Event-Related Potential Evidence

OBJECTIVE This study investigates auditory processing in infants with West syndrome (WS) using event-related potentials (ERPs). METHODS ERPs were measured in 25 infants with mainly symptomatic WS (age range = 3-10 months) and 26 healthy term infants (age range = 3-9 months) using an auditory novelty oddball paradigm. The ERP recordings were made during wakefulness and repeated in stage II sle...

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A measure of auditory prepulse inhibition (PPI) is the reduction of the scalp-recorded P1 event-related potential (ERP) after a sound that is preceded by 100-300 ms by a click as prepulse. This measure of sensory gating was adapted to study the effect of a prepulse on processing tones that were part of a 'go no-go' discrimination. ERPs were recorded at right and left, frontal and temporal sites...

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Quantitative magnetic resonance imaging evidence for altered structural remodeling of the temporal lobe in West syndrome

OBJECTIVE To explore the structure-function relation of the temporal lobe in newly diagnosed West syndrome of unknown cause (uWS). METHODS Quantitative magnetic resonance imaging (three-dimensional [3D] structural MRI and diffusion tensor imaging [DTI]) was analyzed using voxel-based morphometry (VBM) and tract-based spatial statistics (TBSS) in 22 patients and healthy age-matched controls. T...

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Left temporal lobe dysfunction in schizophrenia: event-related potential and behavioral evidence from phonetic and tonal dichotic listening tasks.

BACKGROUND Asymmetric reduction of the P3 event-related potential (ERP) has provided evidence of left temporal lobe dysfunction in schizophrenia. Prior studies have been limited by reliance on simple target detection (oddball) tasks with pure tones. This study investigated the time course and topography of ERPs to binaural syllables or complex tones in dichotic listening tasks. METHODS Event-...

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ژورنال

عنوان ژورنال: Annals of Neurology

سال: 2014

ISSN: 0364-5134

DOI: 10.1002/ana.24297